Cystic Fibrosis
, complicated nature of, as of 1960s
“With each discovery came gradual realization that CF was a complex clinical puzzle and that distinguishing between its primary and secondary features would remain a key conceptual challenge. It was at once a disease of malabsorption, a lung disorder, a pancreatic disease, and a malady defined by an overproduction of mucus” (Waterloo III, 69).