Seige cycle

“Drug career cycles generally encompass three phases: first, an expanding use of the drugs, accompanied by high expectations; then, rising criticism and disappointment; and finally, contracting use and limited application. These phases need not be sequential; they often overlap. . . . Because it was Max Seige who first pointed out the cyclical nature of the careers of psychotropic drugs, we have named this general dynamic a ‘Seige cycle’ (Snelders, Kaplan & Pieters, 97).