1761

Morgagni’s publication, at age 79, of De Sedibus et Causis Morborum per Anatomen Indagatis (On the Seats and Causes of Disease, Investigated by Anatomy), establishing the field of pathological anatomy (Nuland, 63ff.). “Morgagni’s anatomic orientation shifted medical thinking away from a concept of illness as a disruption of humoral equilibrium (a view of illness as a system-wide event) to a concept of illness as a structural disruption in a specific anatomic portion of the body (a view of illness as a localized event” (Reiser II, 904).