1835
Louis, father of the numerical method, publishes his Recherches sur les effets de la saignée dans quelques maladies inflammatoires, which analyzed effects of bloodletting at different stages of pleuropneumonia, erysipelas of the face, and angina tonsillaris and raised questions about its indiscriminate use. James Jackson translated the work and added his own observations of his use of bleeding in 34 cases of pleuropneumonia in Boston (Cassedy, 74). Pliny Earle followed with study of bloodletting in American asylums, and from his own cases at NY’s Bloomingdale Asylum, “that the decreased use of bleeding had been accompanied by an increase in the number of cures” (75).