1841

Jacques-Joseph Moreau published his first article on Cannabis indica; his monograph, Du hachisch et de l’alienation mentale followed in 1845 and launched “the systematic study of the psychological action of psychotropic drugs, which became a model for later research in experimental psychopharmacology and psychopathology. . . . Moreau defined an essential underlying assumption of psychoactive drug research, later described as the ‘psychotomimetic’ view of the effects of psychoactive drugs: namely, the identity of the psychological nature of the delirium in both insanity and drug intoxication” (Snelders, Kaplan & Pieters, 100).