1905

Synthesis of procaine (Novocain) by Alfred Einhorn, working out of Bayer labs, imported into U.S. beginning in 1911 by Novocol, which was licensed to synthesize and manufacture Novocain in U.S. when it entered WWI. As a local anesthetic, it lacked the euphoric and addictive qualities of cocaine. It was replaced in 1943 by lidocaine.