1906

Crile’s first successful case of blood transfusion via end-to-end suturing (Crile I, 165-167). Crile and colleagues begin histologic research showing that shock or exhaustion involved cellular changes in the brain, liver and adrenal glands (188-193). In France, Bergonie and Tribondeau formulate descriptive law about effects of radiation: Its effect greatest on living cells in earliest stage of cell division; it affects reproductive cells most; and it causes proliferation of cancer cells in proportion to their stage of development (Kevles, 52). In Germany, pathologist A. von Wasserman develops his two-stage test for syphilis (Macfarlane, 70).