1989
First publication from Yale-based NIMH studies comparing IPT, CT, imipramine, and “optimal therapeutic encounter” (placebo). It showed that, as severity of depressions increased, both imipramine and interpersonal therapy, but not cognitive therapy, were significantly more effective than clinical management. “The results were very dispiriting to the cognitive therapists, but somewhat more encouraging for Klerman and the advocates of interpersonal therapy” (Healy, 239-245).