1992

Establishment of the Cochrane Centre, based in Oxford and part of Britain’s National Health Service. Cochrane Collaboration was launched in 1993 in Oxford; it now has 49 international review groups, each with a coordinating editor supported by an editorial team that conducted systematic reviews of specific medical topics. Reviews are updated and posted on the Web and also supplied on CD as The Cochrane Library, a database of systematic reviews and controlled trial registers (J. Daly, 167). There are also 14 Cochrane Centres with national or regional responsibilities for coordinating Cochrane initiatives (168). Whereas emphasis at McMaster University was on incorporating evidence from trials into clinical practice, the Cochrane emphasis was on systematic reviews of trials, which provided more reliable evidence for practice (171).